Kalani Residence located in Keramoti, a small town in the Kavala regional unit in northeastern Greece. It is situated on the coast of the Aegean Sea, directly opposite the island of Thassos, which is accessible via a short ferry ride 30min from Keramoti's port. The town is approximately 40 kilometers southeast of Kavala city and about 10 kilometers from the Nestos River Delta, a significant ecological area known for its diverse wildlife and natural beauty.

Keramoti is accessible by road via the E90 highway, which connects it to Kavala and other major cities in the region. There are regular bus services from Kavala to Keramoti, also taxis are readily available. The nearest airport is Kavala International Airport "Megas Alexandros," located about 12 kilometers from Kalani Residence, offering both domestic and international flights.